Which of the following is NOT a symptom of Hepatitis B?

Hepatitis B is known for causing symptoms that primarily affect the liver and overall health. Fatigue, jaundice, and abdominal pain are all common symptoms associated with liver inflammation and infection due to Hepatitis B. Fatigue often arises from the body fighting off the infection, while jaundice occurs when the liver is unable to process bilirubin effectively, leading to a yellowing of the skin and eyes. Abdominal pain may be experienced as a result of liver swelling or discomfort.

In contrast, a headache is not typically associated with Hepatitis B. While headaches can occur for numerous reasons, they do not specifically tie to the liver dysfunction or viral infection characteristic of Hepatitis B. Thus, headache stands out as the symptom that is least likely to be connected to this particular liver disease, making it the correct choice for this question.